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Prescription drugs that have an impact on liver metabolism can cause elevated blood levels of codeine. Will not give along with expectorants, since the far more reproduced mucus can not be coughed off because of the antitussive influence of dihydrocodeine.Sildenafil citrate is often a kind of drug termed a PDE5 inhibitor, which just means that it s

desvenlafaxine will increase the level or effect of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Caution/Keep track of. Desvenlafaxine inhibits CYP2D6; with bigger desvenlafaxine doses (ie, four hundred mg) minimize the CYP2D6 substrate dose by nearly fifty%; no dosage adjustment desired with desvenlafaxine doses 7 consecutive times